Product overview
Description Anti-ALDH1A1/ALDH1A2/ALDH1A3 rabbit polyclonal antibody
Applications ELISA, WB, IHC
Immunogen Fusion protein of human ALDH1A1/ALDH1A2/ALDH1A3
Reactivity Human, Mouse
Content 0.4 mg/ml
Host species Rabbit
Ig class Immunogen-specific rabbit IgG
Purification Antigen affinity purification
Anti-ALDH1A1/ALDH1A2/ALDH1A3 antibody Target information
Symbol ALDH1A1/ALDH1A2/ALDH1A3
Full name Aldehyde dehydrogenase 1 family, member A1/2/3
Synonyms ALDC, ALDH1, PUMB1, ALDH11, RALDH1, ALDH-E1; RALDH2, RALDH2-T, RALDH(II); ALDH6, RALDH3, ALDH1A6
Swissprot P00352/O94788/P47895
Target Background
This protein belongs to the aldehyde dehydrogenase family of proteins. The product of this gene is an enzyme that catalyzes the synthesis of retinoic acid (RA) from retinaldehyde. Retinoic acid, the active derivative of vitamin A (retinol), is a hormonal signaling molecule that functions in developing and adult tissues. The studies of a similar mouse gene suggest that this enzyme and the cytochrome CYP26A1, concurrently establish local embryonic retinoic acid levels which facilitate posterior organ development and prevent spina bifida. Four transcript variants encoding distinct isoforms have been identified for this gene.
Anti-ALDH1A1/ALDH1A2/ALDH1A3 antibody Applications
Immunohistochemistry
Predicted cell location: Cytoplasm
Positive control: Human liver cancer
Recommended dilution: 50-150