Product overview Description Anti-ARL17 rabbit polyclonal antibody
Applications ELISA, IHC
Immunogen Fusion protein of human ARL17
Reactivity Human
Content 0.5 mg/ml
Host species Rabbit
Ig class Immunogen-specific rabbit IgG
Purification Antigen affinity purification
Target information Symbol ARL17
Full name ADP-ribosylation factor-like 17A/ADP-ribosylation factor-like 17B
Synonyms ARF1P2; ARL17P1/ARL17; ARL17A
Swissprot Q8IVW1
Target Background ARL17 (ADP-ribosylation factor-like protein 17), also known as ARF1P2 or ARL17P1, is a 177 amino acid member of the ARF protein family. In human, there are two genes which have been identified as ARL17A and ARL17B that code for identical proteins and colocalize at chromosomal position 17q21.31. ARL17 functions as an activator of the cholera toxin catalytic subunit, an ADP-ribosyltransferase. Localized to the Golgi apparatus, ARL17 may also be involved in the modulation of vesicle budding and uncoating within the Golgi. ARL17 is expressed as three isoforms produced by alternative splicing events.GTP-binding protein that functions as an allosteric activator of the cholera toxin catalytic subunit, an ADP-ribosyltransferase. Involved in protein trafficking; may modulate vesicle budding and uncoating within the Golgi apparatus (By similarity).
Applications Immunohistochemistry
Predicted cell location: Cytoplasm and Nucleus
Positive control: Human thyroid cancer
Recommended dilution: 25-100 Predicted cell location: Cytoplasm and Nucleus
Positive control: Human brain
Recommended dilution: 25-100