- 询价
- gelatins
- JC164150
- 进口/国产
- 2025年07月12日
- ELISA, WB
- Rabbit
- 人/动物/植物
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- 详细信息
- 技术资料
- 供应商：
上海机纯实业有限公司
- 库存：
大量
- 克隆性：
多克隆
- 保质期：
12个月
- 抗体英文名：
Anti-MOB2 antibody
- 宿主：
Rabbit
- 适应物种：
人/动物/植物
- 应用范围：
ELISA, WB
- 浓度：
0.6 mg/ml
- 保存条件：
-20°C
- 规格：
25 μl/100 μl/200 μl
Anti-MOB2 antibody
Cat. No. JC164150
Package 25 μl/100 μl/200 μl
Storage -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Product overview
Description Anti-MOB2 rabbit polyclonal antibody
Applications ELISA, IHC
Immunogen Synthetic peptide of human MOB2
Reactivity Human, Mouse
Content 0.6 mg/ml
Host species Rabbit
Ig class Immunogen-specific rabbit IgG
Purification Antigen affinity purification
Anti-MOB2 antibody
Target information
Symbol MOB2
Full name MOB kinase activator 2
Synonyms HCCA2
Swissprot Q70IA6
Target Background
MOB2 (Mps one binder kinase activator-like 2), also known as HCCA2 (Hepatocellular carcinoma-associated gene 2), is a 467 amino acid protein that belongs to the MOB1/phocein family. MOB2 is expressed in lung, spleen, brain, and fetal liver. It is highly expressed in hepatocellular carcinoma. MOB2 is localized in the perinuclear region of the cytoplasm in liver cancer tissues and colocalizes with MAD2L2 in the nucleus of Hela cells. MOB2 is characterized by two N-glycosylation sites, six N-myristolylation sites, two Src homology 3 (SH3), and several phosphorylation motifs which indicate that this protein may play a role in an intracellular signal transduction cascade. MOB2 binds to and regulates the autophosphorylation of the related human serine/threonine kinase 38 (NDR1) and serine/threonine kinase 38L(NDR2). It has been shown that MOB2 plays a critical role in cell cycle regulation. Overexpression of the protein during the G0/G1 phase inhibits cell proliferation causing cell cycle arrest. Stimulates the autophosphorylation and kinase activity of STK38 and STK38L.
Anti-MOB2 antibody
Applications
Immunohistochemistry
Predicted cell location: Cytoplasm
Positive control: Human liver cancer
Recommended dilution: 20-100 Predicted cell location: Cytoplasm
Positive control: Human thyroid cancer
Recommended dilution: 20-100
Cat. No. JC164150
Package 25 μl/100 μl/200 μl
Storage -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Product overview
Description Anti-MOB2 rabbit polyclonal antibody
Applications ELISA, IHC
Immunogen Synthetic peptide of human MOB2
Reactivity Human, Mouse
Content 0.6 mg/ml
Host species Rabbit
Ig class Immunogen-specific rabbit IgG
Purification Antigen affinity purification
Anti-MOB2 antibody
Target information
Symbol MOB2
Full name MOB kinase activator 2
Synonyms HCCA2
Swissprot Q70IA6
Target Background
MOB2 (Mps one binder kinase activator-like 2), also known as HCCA2 (Hepatocellular carcinoma-associated gene 2), is a 467 amino acid protein that belongs to the MOB1/phocein family. MOB2 is expressed in lung, spleen, brain, and fetal liver. It is highly expressed in hepatocellular carcinoma. MOB2 is localized in the perinuclear region of the cytoplasm in liver cancer tissues and colocalizes with MAD2L2 in the nucleus of Hela cells. MOB2 is characterized by two N-glycosylation sites, six N-myristolylation sites, two Src homology 3 (SH3), and several phosphorylation motifs which indicate that this protein may play a role in an intracellular signal transduction cascade. MOB2 binds to and regulates the autophosphorylation of the related human serine/threonine kinase 38 (NDR1) and serine/threonine kinase 38L(NDR2). It has been shown that MOB2 plays a critical role in cell cycle regulation. Overexpression of the protein during the G0/G1 phase inhibits cell proliferation causing cell cycle arrest. Stimulates the autophosphorylation and kinase activity of STK38 and STK38L.
Anti-MOB2 antibody
Applications
Immunohistochemistry
Predicted cell location: Cytoplasm
Positive control: Human liver cancer
Recommended dilution: 20-100 Predicted cell location: Cytoplasm
Positive control: Human thyroid cancer
Recommended dilution: 20-100
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Anti-MOB2 antibody
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