Anti-GP6 antibody

Anti-GP6 antibody

Cat. No.     JC164003
Package    25 μl/100 μl/200 μl
Storage    -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol

Product overview
Description                   Anti-GP6 rabbit polyclonal antibody
Applications        ELISA, WB, IHC 
Immunogen               Synthetic peptide of human GP6
Reactivity                 Human
Content                     1.44 mg/ml
Host species               Rabbit
Ig class                  Immunogen-specific rabbit IgG
Purification                 Antigen affinity purification

Anti-GP6 antibody
Target information
Symbol                 GP6
Full name                 glycoprotein VI platelet
Synonyms    GPIV; GPVI; BDPLT11
Swissprot    Q9HCN6

Target Background
This gene encodes a platelet membrane glycoprotein of the immunoglobulin superfamily. The encoded protein is a receptor for collagen and plays a critical role in collagen-induced platelet aggregation and thrombus formation. The encoded protein forms a complex with the Fc receptor gamma-chain that initiates the platelet activation signaling cascade upon collagen binding. Mutations in this gene are a cause of platelet-type bleeding disorder-11 (BDPLT11). Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

Anti-GP6 antibody
Applications
Immunohistochemistry
Predicted cell location: Cell membrane
Positive control: Human colorectal cancer
Recommended dilution: 50-300    Predicted cell location: Cell membrane
Positive control: Human thyroid cancer
Recommended dilution: 50-300