Anti-EFHD2 antibody

Anti-EFHD2 antibody

Cat. No.    JC163761
Package    25 μl/100 μl/200 μl
Storage    -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol

Product overview
Description                   Anti-EFHD2 rabbit polyclonal antibody
Applications        ELISA, WB 
Immunogen               Synthetic peptide of human EFHD2
Reactivity                 Human, Mouse, Rat
Content                     0.84 mg/ml
Host species               Rabbit
Ig class                  Immunogen-specific rabbit IgG
Purification                 Antigen affinity purification

Anti-EFHD2 antibody
Target information
Symbol                 EFHD2
Full name                 EF-hand domain family member D2
Synonyms    SWS1
Swissprot    Q96C19

Target Background
EFHD2 is a calcium-binding adaptor protein associated with pathologically aggregated tau in Alzheimer disease brain and in a mouse model of frontotemporal dementia. EFHD2 has cell type-specific functions, including modulation of intracellular calcium responses, actin dynamics, and microtubule transport. May regulate B-cell receptor (BCR)-induced immature and primary B-cell apoptosis. Plays a role as negative regulator of the canonical NF-kappa-B-activating branch. Controls spontaneous apoptosis through the regulation of BCL2L1 abundance.

Anti-EFHD2 antibody
Applications
Western blotting
Predicted band size:27 kDa
Positive control:A549 cell lysate 
Recommended dilution: 200-1000