Product overview
Description Anti-POT1 rabbit polyclonal antibody
Applications ELISA, IHC
Immunogen Fusion protein of human POT1
Reactivity Human
Content 0.3 mg/ml
Host species Rabbit
Ig class Immunogen-specific rabbit IgG
Purification Antigen affinity purification
Anti-POT1 antibody Target information
Symbol POT1
Full name protection of telomeres 1
Synonyms CMM10; HPOT1
Swissprot Q9NUX5
Target Background
This gene is a member of the telombin family and encodes a nuclear protein involved in telomere maintenance. Specifically, this protein functions as a member of a multi-protein complex that binds to the TTAGGG repeats of telomeres, regulating telomere length and protecting chromosome ends from illegitimate recombination, catastrophic chromosome instability, and abnormal chromosome segregation. Increased transcriptional expression of this gene is associated with stomach carcinogenesis and its progression. Alternatively spliced transcript variants have been described.
Anti-POT1 antibody Applications
Immunohistochemistry
Predicted cell location: Nucleus
Positive control: Human colorectal cancer
Recommended dilution: 25-100 Predicted cell location: Nucleus
Positive control: Human esophagus cancer
Recommended dilution: 25-100