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- 详细信息
- 技术资料
- 保存条件:
零下80~20°C
- 保质期:
Powder: -20°C for 3 years In solvent: -80°C for 2 years
- 英文名:
Corylifol A
- 库存:
10
- 供应商:
TargetMol
- CAS号:
775351-88-7
- 规格:
5 mg/1 mL/10 mg/100 mg/50 mg/1 mg/500 mg/25 mg
| 规格: | 5 mg | 产品价格: | ¥1230.0 |
|---|---|---|---|
| 规格: | 1 mL | 产品价格: | ¥1370.0 |
| 规格: | 10 mg | 产品价格: | ¥1990.0 |
| 规格: | 100 mg | 产品价格: | ¥6680.0 |
| 规格: | 50 mg | 产品价格: | ¥4820.0 |
| 规格: | 1 mg | 产品价格: | ¥518.0 |
| 规格: | 500 mg | 产品价格: | ¥13300.0 |
| 规格: | 25 mg | 产品价格: | ¥3380.0 |
Product Introduction
Bioactivity
英文名:Corylifol A
描述:1. Corylifol A (Corylinin) displays cytotoxic activity against HepG2 and Hep3B hepatocellular carcinoma cell lines, with IC50 values of 4.6 and 13.5 ug/ml, respectively. 2. Corylifol A and Biochanin A can be the potential uncouplers of neuronal nitric oxide synthase-postsynaptic density protein-95. 3. Corylifol A and bavachin are strong inhibitors of UDP-glucuronosyltransferase 1A1 (UGT1A1) with the inhibition kinetic parameters (Ki) values lower than 1 uM.4. Corylifol A and bakuchiol are naturally occurring potent inhibitors of hCE2, with low Ki values ranging from 0.62uM to 3.89 uM. 5. Corylifol A shows an inhibitory effect on IL-6-induced STAT3 promoter activity in Hep3B cells with IC50 values of 0.81 ± 0.15 uμ, it also inhibits STAT3 phosphorylation induced by IL-6 in Hep3B cells, suggests that corylifol A has antiinflammatory activity.

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