Product overview
Description Anti-MST1R rabbit polyclonal antibody
Applications ELISA, IHC
Immunogen Synthetic peptide of human MST1R
Reactivity Human
Content 1.5 mg/ml
Host species Rabbit
Ig class Immunogen-specific rabbit IgG
Purification Antigen affinity purification
Anti-MST1R antibody Target information
Symbol MST1R
Full name macrophage stimulating 1 receptor
Synonyms RON; PTK8; CD136; CDw136
Swissprot Q04912
Target Background
This gene encodes a cell surface receptor for macrophage-stimulating protein (MSP) with tyrosine kinase activity. The mature form of this protein is a heterodimer of disulfide-linked alpha and beta subunits, generated by proteolytic cleavage of a single-chain precursor. The beta subunit undergoes tyrosine phosphorylation upon stimulation by MSP. This protein is expressed on the ciliated epithelia of the mucociliary transport apparatus of the lung, and together with MSP, thought to be involved in host defense. Alternative splicing generates multiple transcript variants encoding different isoforms that may undergo similar proteolytic processing.
Anti-MST1R antibody Applications
Immunohistochemistry
Predicted cell location: Cytoplasm and Cell membrane
Positive control: Human liver cancer
Recommended dilution: 25-100