Product overview Description Anti-OTC rabbit polyclonal antibody
Applications ELISA, WB, IHC
Immunogen Fusion protein of human OTC
Reactivity Human, Mouse, Rat
Content 0.3 mg/ml
Host species Rabbit
Ig class Immunogen-specific rabbit IgG
Purification Antigen affinity purification
Target information Symbol OTC
Full name ornithine carbamoyltransferase
Synonyms OCTD
Swissprot P00480
Target Background This nuclear gene encodes a mitochondrial matrix enzyme. Missense, nonsense, and frameshift mutations in this enzyme lead to ornithine transcarbamylase deficiency, which causes hyperammonemia. Since the gene for this enzyme maps close to that for Duchenne muscular dystrophy, it may play a role in that disease also.
Applications Immunohistochemistry
Predicted cell location: Cytoplasm
Positive control: Human colon cancer
Recommended dilution: 50-200 Predicted cell location: Cytoplasm
Positive control: Human tonsil
Recommended dilution: 50-200