Product overview Description Anti-PVRL4 rabbit polyclonal antibody
Applications ELISA, IHC
Immunogen Fusion protein of human PVRL4
Reactivity Human, Mouse
Content 0.4 mg/ml
Host species Rabbit
Ig class Immunogen-specific rabbit IgG
Purification Antigen affinity purification
Target information Symbol PVRL4
Full name poliovirus receptor-related 4
Synonyms LNIR; PRR4; EDSS1; nectin-4
Swissprot Q96NY8
Target Background This gene encodes a member of the nectin family. The encoded protein contains two immunoglobulin-like (Ig-like) C2-type domains and one Ig-like V-type domain. It is involved in cell adhesion through trans-homophilic and -heterophilic interactions. It is a single-pass type I membrane protein. The soluble form is produced by proteolytic cleavage at the cell surface by the metalloproteinase ADAM17/TACE. The secreted form is found in both breast tumor cell lines and breast tumor patients.
Applications Immunohistochemistry
Predicted cell location: Cytoplasm
Positive control: Human colon cancer
Recommended dilution: 50-200 Predicted cell location: Cytoplasm
Positive control: Human liver cancer
Recommended dilution: 50-200