- 询价
- gelatins
- JC163508
- 进口/国产
- 2025年07月16日
- ELISA, WB
- Rabbit
- 人/动物/植物
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- 详细信息
- 文献和实验
- 技术资料
- 供应商：
上海机纯实业有限公司
- 库存：
大量
- 克隆性：
多克隆
- 保质期：
12个月
- 抗体英文名：
Anti-TNFSF11 antibody
- 宿主：
Rabbit
- 适应物种：
人/动物/植物
- 应用范围：
ELISA, WB
- 浓度：
0.66 mg/ml
- 保存条件：
-20°C
- 规格：
25 μl/100 μl/200 μl
Cat. No. JC163508
Package 25 μl/100 μl/200 μl
Storage -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Product overview
Description Anti-TNFSF11 rabbit polyclonal antibody
Applications ELISA, IHC
Immunogen Synthetic peptide of human TNFSF11
Reactivity Human, Mouse, Rat
Content 0.66 mg/ml
Host species Rabbit
Ig class Immunogen-specific rabbit IgG
Purification Antigen affinity purification
Anti-TNFSF11 antibody
Target information
Symbol TNFSF11
Full name tumor necrosis factor superfamily member 11
Synonyms ODF; OPGL; sOdf; CD254; OPTB2; RANKL; TNLG6B; TRANCE; hRANKL2
Swissprot O14788
Target Background
This gene encodes a member of the tumor necrosis factor (TNF) cytokine family which is a ligand for osteoprotegerin and functions as a key factor for osteoclast differentiation and activation. This protein was shown to be a dentritic cell survival factor and is involved in the regulation of T cell-dependent immune response. T cell activation was reported to induce expression of this gene and lead to an increase of osteoclastogenesis and bone loss. This protein was shown to activate antiapoptotic kinase AKT/PKB through a signaling complex involving SRC kinase and tumor necrosis factor receptor-associated factor (TRAF) 6, which indicated this protein may have a role in the regulation of cell apoptosis. Targeted disruption of the related gene in mice led to severe osteopetrosis and a lack of osteoclasts. The deficient mice exhibited defects in early differentiation of T and B lymphocytes, and failed to form lobulo-alveolar mammary structures during pregnancy. Two alternatively spliced transcript variants have been found.
Anti-TNFSF11 antibody
Applications
Immunohistochemistry
Predicted cell location: Cytoplasm
Positive control: Human esophagus cancer
Recommended dilution: 20-100 Predicted cell location: Cytoplasm
Positive control: Human brain
Recommended dilution: 20-100
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文献和实验a simple ELISA method to detect human anti-antibody response.
Purification Of Anti Peptide Antibody
antibody that could contribute to staining background. The proportion in each pool varies with the peptide immunogen. The quality of the anti-peptide serum seems to increase with multiple boosts - the first bleed may be feeble.
Anticardiolipin Antibody and Anti-beta 2 Glycoprotein I Antibody Assays
standard” laboratory test to diagnose or classify a patient as having APS. This chapter discusses the clinical and laboratory theoretical and technical aspects of aCL and anti-β2GPI antibody assays.
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