Product overview
Description Anti-CACNA1B rabbit polyclonal antibody
Applications ELISA, IHC
Immunogen Synthetic peptide of human CACNA1B
Reactivity Human, Mouse, Rat
Content 0.2 mg/ml
Host species Rabbit
Ig class Immunogen-specific rabbit IgG
Purification Antigen affinity purification
Target information
Symbol CACNA1B
Full name calcium voltage-gated channel subunit alpha1 B
Synonyms BIII; CACNN; DYT23; Cav2.2; CACNL1A5
Swissprot Q00975
Target Background
The protein encoded by this gene is the pore-forming subunit of an N-type voltage-dependent calcium channel, which controls neurotransmitter release from neurons. The encoded protein forms a complex with alpha-2, beta, and delta subunits to form the high-voltage activated channel. This channel is sensitive to omega-conotoxin-GVIA and omega-agatoxin-IIIA but insensitive to dihydropyridines. Two transcript variants encoding different isoforms have been found for this gene.