Product overview
Description Anti-C3/C3b rabbit polyclonal antibody
Applications ELISA, IHC
Immunogen Synthetic peptide of human C3/C3b
Reactivity Human, Mouse, Rat
Content 0.4 mg/ml
Host species Rabbit
Ig class Immunogen-specific rabbit IgG
Purification Antigen affinity purification
Anti-C3/C3b antibody Target information
Symbol C3/C3b
Full name complement component 3
Synonyms ASP; C3a; C3b; AHUS5; ARMD9; CPAMD1; HEL-S-62p
Swissprot P01024
Target Background
Complement component C3 plays a central role in the activation of complement system. Its activation is required for both classical and alternative complement activation pathways. The encoded preproprotein is proteolytically processed to generate alpha and beta subunits that form the mature protein, which is then further processed to generate numerous peptide products. The C3a peptide, also known as the C3a anaphylatoxin, modulates inflammation and possesses antimicrobial activity. Mutations in this gene are associated with atypical hemolytic uremic syndrome and age-related macular degeneration in human patients.
Anti-C3/C3b antibody Applications
Immunohistochemistry
Predicted cell location: Cytoplasm and Cell membrane
Positive control: Human liver cancer
Recommended dilution: 25-100 Predicted cell location: Cytoplasm and Cell membrane
Positive control: Human breast cancer
Recommended dilution: 25-100