Product overview
Description Anti-KLK8 rabbit polyclonal antibody
Applications ELISA, IHC
Immunogen Fusion protein of human KLK8
Reactivity Human
Content 0.2 mg/ml
Host species Rabbit
Ig class Immunogen-specific rabbit IgG
Purification Antigen affinity purification
Anti-KLK8 antibody Target information
Symbol KLK8
Full name kallikrein-related peptidase 8
Synonyms NP; HNP; NRPN; PRSS19; TADG14
Swissprot O60259
Target Background
Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen kallikrein subfamily members located in tandem in a gene cluster on chromosome 19. The encoded protein may be involved in proteolytic cascade in the skin and may serve as a biomarker for ovarian cancer. Alternate splicing of this gene results in multiple transcript variants encoding different isoforms.
Anti-KLK8 antibody Applications
Immunohistochemistry
Predicted cell location: Cytoplasm
Positive control: Human thyroid cancer
Recommended dilution: 25-100 Predicted cell location: Cytoplasm
Positive control: Human esophagus cancer
Recommended dilution: 25-100