Product overview
Description Anti-CNGA2 rabbit polyclonal antibody
Applications ELISA, IHC
Immunogen Fusion protein of human CNGA2
Reactivity Human, Mouse, Rat
Content 0.4 mg/ml
Host species Rabbit
Ig class Immunogen-specific rabbit IgG
Purification Antigen affinity purification
Target information
Symbol CNGA2
Full name cyclic nucleotide gated channel alpha 2
Synonyms CNCA, CNG2, CNCA1, OCNC1, OCNCa, OCNCALPHA
Swissprot Q16280
Target Background
The protein encoded by this gene represents the alpha subunit of a cyclic nucleotide-gated olfactory channel. The encoded protein contains a carboxy-terminal leucine zipper that mediates channel formation. Odorant signal transduction is probably mediated by a G-protein coupled cascade using cAMP as second messenger. The olfactory channel can be shown to be activated by cyclic nucleotides which leads to a depolarization of olfactory sensory neurons.