Product overview
Description Anti-FOS rabbit polyclonal antibody
Applications ELISA, WB
Immunogen Fusion protein of human FOS
Reactivity Human, Mouse, Rat
Content 1.5 mg/ml
Host species Rabbit
Ig class Immunogen-specific rabbit IgG
Purification Antigen affinity purification
Target information
Symbol FOS
Full name Fos proto-oncogene, AP-1 transcription factor subunit
Synonyms p55; AP-1; C-FOS
Swissprot P01100
Target Background
The Fos gene family consists of 4 members: FOS, FOSB, FOSL1, and FOSL2. These genes encode leucine zipper proteins that can dimerize with proteins of the JUN family, thereby forming the transcription factor complex AP-1. As such, the FOS proteins have been implicated as regulators of cell proliferation, differentiation, and transformation. In some cases, expression of the FOS gene has also been associated with apoptotic cell death.