Product overview
Description Anti-CEBPE rabbit polyclonal antibody
Applications ELISA, WB
Immunogen Fusion protein of human CEBPE
Reactivity Human, Mouse, Rat
Content 0.3 mg/ml
Host species Rabbit
Ig class Immunogen-specific rabbit IgG
Purification Antigen affinity purification
Target information
Symbol CEBPE
Full name CCAAT/enhancer binding protein (C/EBP), epsilon
Synonyms CRP1; C/EBP-epsilon
Swissprot Q15744
Target Background
The protein encoded by this gene is a bZIP transcription factor which can bind as a homodimer to certain DNA regulatory regions. It can also form heterodimers with the related protein CEBP-delta. The encoded protein may be essential for terminal differentiation and functional maturation of committed granulocyte progenitor cells. Mutations in this gene have been associated with Specific Granule Deficiency, a rare congenital disorder. Multiple variants of this gene have been described, but the full-length nature of only one has been determined.