Product overview
Description Anti-CEACAM8 rabbit polyclonal antibody
Applications ELISA, IHC
Immunogen Fusion protein of human CEACAM8
Reactivity Human
Content 0.4 mg/ml
Host species Rabbit
Ig class Immunogen-specific rabbit IgG
Purification Antigen affinity purification
Target information
Symbol CEACAM8
Full name carcinoembryonic antigen related cell adhesion molecule 8
Synonyms CD67; CGM6; CD66b; NCA-95
Swissprot P31997
Target Background
CEA-related cell adhesion molecule 8 (CEACAM8) belongs to the carcinoembryonic antigen (CEA) gene family. It encodes a glycosylphosphatidylinositol (GPI)-linked glycoprotein with a molecular mass of of 95kD and is expressed in cells of the granulocyte-lineage. It is expressed in neutrophils and eosinophils and is characterized as a granulocyte-specific activation antigen. Therefore CEACAM8 could serve as a marker for granulocyte activities. Like all members of the CEA family, it consists of a single N domain, with structural homology to the immunoglobulin variable domains, followed by two immunoglobulin constant-like A and B domains.