Product overview
Description Anti-CTSH rabbit polyclonal antibody
Applications ELISA, IHC
Immunogen Fusion protein of human CTSH
Reactivity Human, Mouse, Rat
Content 1 mg/ml
Host species Rabbit
Ig class Immunogen-specific rabbit IgG
Purification Antigen affinity purification
Target information
Symbol CTSH
Full name cathepsin H
Synonyms CPSB; ACC-4; ACC-5; minichain
Swissprot P09668
Target Background
The protein encoded by this gene is a lysosomal cysteine proteinase important in the overall degradation of lysosomal proteins. It is composed of a dimer of disulfide-linked heavy and light chains, both produced from a single protein precursor. The encoded protein, which belongs to the peptidase C1 protein family, can act both as an aminopeptidase and as an endopeptidase. Increased expression of this gene has been correlated with malignant progression of prostate tumors.