Product overview
Description Anti-CAMK2B rabbit polyclonal antibody
Applications ELISA, IHC
Immunogen Fusion protein of human CAMK2B
Reactivity Human, Mouse, Rat
Content 0.3 mg/ml
Host species Rabbit
Ig class Immunogen-specific rabbit IgG
Purification Antigen affinity purification
Target information
Symbol CAMK2B
Full name Calcium/calmodulin-dependent protein kinase type II subunit beta
Synonyms CAM2, CAMK2, CAMKB
Swissprot Q13554
Target Background
The product of this gene belongs to the serine/threonine protein kinase family and to the Ca(2+)/calmodulin-dependent protein kinase subfamily. Calcium signaling is crucial for several aspects of plasticity at glutamatergic synapses. In mammalian cells, the enzyme is composed of four different chains: alpha, beta, gamma, and delta. The product of this gene is a beta chain. It is possible that distinct isoforms of this chain have different cellular localizations and interact differently with calmodulin. Eight transcript variants encoding eight distinct isoforms have been identified for this gene.