Product overview
Description Anti-CAPN5 rabbit polyclonal antibody
Applications ELISA, WB, IHC
Immunogen Fusion protein of human CAPN5
Reactivity Human, Mouse, Rat
Content 0.6 mg/ml
Host species Rabbit
Ig class Immunogen-specific rabbit IgG
Purification Antigen affinity purification
Target information
Symbol CAPN5
Full name calpain 5
Synonyms VRNI; ADNIV; HTRA3; nCL-3
Swissprot O15484
Target Background
Calpains are calcium-dependent cysteine proteases involved in signal transduction in a variety of cellular processes. A functional calpain protein consists of an invariant small subunit and 1 of a family of large subunits. CAPN5 is one of the large subunits. Unlike some of the calpains, CAPN5 and CAPN6 lack a calmodulin-like domain IV. Because of the significant similarity to Caenorhabditis elegans sex determination gene tra-3, CAPN5 is also called as HTRA3.