Product overview
Description Anti-ANGPT2 rabbit polyclonal antibody
Applications ELISA, IHC
Immunogen Fusion protein of human ANGPT2
Reactivity Human, Mouse, Rat
Content 0.2 mg/ml
Host species Rabbit
Ig class Immunogen-specific rabbit IgG
Purification Antigen affinity purification
Target information
Symbol ANGPT2
Full name angiopoietin 2
Synonyms ANG2; AGPT2
Swissprot O15123
Target Background
The protein encoded by this gene is an antagonist of angiopoietin 1 (ANGPT1) and endothelial TEK tyrosine kinase (TIE-2, TEK). The encoded protein disrupts the vascular remodeling ability of ANGPT1 and may induce endothelial cell apoptosis. Three transcript variants encoding three different isoforms have been found for this gene.