Product overview Description Anti-CRELD2 rabbit polyclonal antibody
Applications ELISA, WB, IHC
Immunogen Fusion protein of human CRELD2
Reactivity Human
Content 0.3 mg/ml
Host species Rabbit
Ig class Immunogen-specific rabbit IgG
Purification Antigen affinity purification
Target information Symbol CRELD2
Full name cysteine-rich with EGF-like domains 2
Synonyms
Swissprot Q6UXH1
Target Background CRELD2 (cysteine-rich with EGF-like domains 2) is a 353 amino acid protein that is ubiquitously expressed and contains two FU domains and two EGF-like domains. Localized to the endoplasmic reticulum and secreted into the cell, CRELD2 interacts with AChRå4, possibly regulating its transport. Human CRELD2 shares 69% amino acid identity with its mouse counterpart, suggesting a conserved role between species. Multiple isoforms of CRELD2 exist due to alternative splicing events. The gene encoding CRELD2 maps to human chromosome 22, which houses over 500 genes and is the second smallest human chromosome.
Applications Immunohistochemistry
Predicted cell location: Cytoplasm
Positive control: Human cervical cancer
Recommended dilution: 50-200 Predicted cell location: Cytoplasm
Positive control: Human thyroid cancer
Recommended dilution: 50-200