Product overview
Description Anti-AGR2 rabbit polyclonal antibody
Applications ELISA, WB, IHC
Immunogen Fusion protein of human AGR2
Reactivity Human, Mouse
Content 0.7 mg/ml
Host species Rabbit
Ig class Immunogen-specific rabbit IgG
Purification Antigen affinity purification
Target information
Symbol AGR2
Full name Anterior gradient protein 2 homolog
Synonyms AG2, GOB-4, HAG-2, XAG-2, PDIA17
Swissprot O95994
Target Background
Anterior gradient protein 2 homolog (AGR2) is a human protein originally discovered in Xenopus laevis, encoded for by the gene of the same name.In Xenopus AGR2 is an important role in cement gland differentiation, however in human cancer cell lines high levels of AGR2 correlate with reduction of the p53 response and AGR2 levels are elevated in the preneoplastic tissue Barrett's oesophagus.