Product overview
Description Anti-KLK3 rabbit polyclonal antibody
Applications ELISA, IHC
Immunogen Fusion protein of human KLK3
Reactivity Human
Content 0.5 mg/ml
Host species Rabbit
Ig class Immunogen-specific rabbit IgG
Purification Antigen affinity purification
Target information
Symbol KLK3
Full name Kallikrein-3
Synonyms APS, PSA
Swissprot P07288
Target Background
KLK3 is a member of the kallikrein-related peptidase family secreted by the epithelial cells of the prostate gland and lead to the liquefaction of the seminal coagulum. It is thought to function normally in the liquefaction of seminal coagulum, presumably by hydrolysis of the high molecular mass seminal vesicle protein. Serum level of this protein, called PSA in the clinical setting, is useful in the diagnosis and monitoring of prostatic carcinoma.