Product overview
Description Anti-SLC12A5 rabbit polyclonal antibody
Applications ELISA, IHC
Immunogen Synthetic peptide of human SLC12A5
Reactivity Human, Mouse, Rat
Content 1.44 mg/ml
Host species Rabbit
Ig class Immunogen-specific rabbit IgG
Purification Antigen affinity purification
Target information
Symbol SLC12A5
Full name solute carrier family 12 member 5
Synonyms KCC2; EIG14; hKCC2; EIEE34
Swissprot Q9H2X9
Target Background
K-Cl cotransporters are proteins that lower intracellular chloride concentrations below the electrochemical equilibrium potential. The protein encoded by this gene is an integral membrane K-Cl cotransporter that can function in either a net efflux or influx pathway, depending on the chemical concentration gradients of potassium and chloride. The encoded protein can act as a homomultimer, or as a heteromultimer with other K-Cl cotransporters, to maintain chloride homeostasis in neurons. Alternative splicing results in two transcript variants encoding different isoforms.