Product overview Description Anti-ENO1 rabbit polyclonal antibody
Applications ELISA, WB, IHC
Immunogen Fusion protein of human ENO1
Reactivity Human, Mouse, Rat
Content 0.4 mg/ml
Host species Rabbit
Ig class Immunogen-specific rabbit IgG
Purification Antigen affinity purification
Target information Symbol ENO1
Full name enolase 1, (alpha)
Synonyms NNE; PPH; MPB1; ENO1L1
Swissprot P06733
Target Background This gene encodes alpha-enolase, one of three enolase isoenzymes found in mammals. Each isoenzyme is a homodimer composed of 2 alpha, 2 gamma, or 2 beta subunits, and functions as a glycolytic enzyme. Alpha-enolase in addition, functions as a structural lens protein (tau-crystallin) in the monomeric form. Alternative splicing of this gene results in a shorter isoform that has been shown to bind to the c-myc promoter and function as a tumor suppressor. Several pseudogenes have been identified, including one on the long arm of chromosome 1. Alpha-enolase has also been identified as an autoantigen in Hashimoto encephalopathy.
Applications Immunohistochemistry
Predicted cell location: Cytoplasm
Positive control: Human liver cancer
Recommended dilution: 50-200 Predicted cell location: Cytoplasm
Positive control: Human thyroid cancer
Recommended dilution: 50-200