Anti-ALPP antibody

Anti-ALPP antibody

Cat. No.     JC221938
Package    25 μl/100 μl/200 μl
Storage    -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol

Product overview
Description                   Anti-ALPP rabbit polyclonal antibody
Applications        ELISA, WB, IHC 
Immunogen               Fusion protein of human ALPP
Reactivity                 Human
Content                     0.842 mg/ml
Host species               Rabbit
Ig class                  Immunogen-specific rabbit IgG
Purification                 Antigen affinity purification

Target information
Symbol                 ALPP
Full name                 alkaline phosphatase, placental
Synonyms    ALP; PALP; PLAP; PLAP-1
Swissprot    P05187

Target Background
There are at least four distinct but related alkaline phosphatases: intestinal, placental, placental-like, and liver/bone/kidney (tissue non-specific). The first three are located together on chromosome 2 while the tissue non-specific form is located on chromosome 1. The product of this gene is a membrane bound glycosylated enzyme, also referred to as the heat stable form, that is expressed primarily in the placenta although it is closely related to the intestinal form of the enzyme as well as to the placental-like form. The coding sequence for this form of alkaline phosphatase is unique in that the 3' untranslated region contains multiple copies of an Alu family repeat. In addition, this gene is polymorphic and three common alleles (type 1, type 2 and type 3) for this form of alkaline phosphatase have been well characterized.

Applications
Immunohistochemistry
Predicted cell location: Cytoplasm
Positive control: Human lung cancer
Recommended dilution: 50-200    Predicted cell location: Cytoplasm
Positive control: Human thyroid cancer
Recommended dilution: 50-200