Anti-PIP4K2A antibody

Anti-PIP4K2A antibody

Cat. No.     JC221897
Package    25 μl/100 μl/200 μl
Storage    -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol

Product overview
Description                   Anti-PIP4K2A rabbit polyclonal antibody
Applications        ELISA, WB, IHC 
Immunogen               Fusion protein of human PIP4K2A
Reactivity                 Human, Mouse, Rat
Content                     0.4 mg/ml
Host species               Rabbit
Ig class                  Immunogen-specific rabbit IgG
Purification                 Antigen affinity purification

Target information
Symbol                 PIP4K2A
Full name                 phosphatidylinositol-5-phosphate 4-kinase, type II, alpha
Synonyms    PIPK; PI5P4KA; PIP5K2A; PIP5KIIA; PIP5KII-alpha
Swissprot    P48426

Target Background
Phosphatidylinositol-5,4-bisphosphate, the precursor to second messengers of the phosphoinositide signal transduction pathways, is thought to be involved in the regulation of secretion, cell proliferation, differentiation, and motility. The protein encoded by this gene is one of a family of enzymes capable of catalyzing the phosphorylation of phosphatidylinositol-5-phosphate on the fourth hydroxyl of the myo-inositol ring to form phosphatidylinositol-5,4-bisphosphate. The amino acid sequence of this enzyme does not show homology to other kinases, but the recombinant protein does exhibit kinase activity. This gene is a member of the phosphatidylinositol-5-phosphate 4-kinase family.

Applications
Immunohistochemistry
Predicted cell location: Cytoplasm
Positive control: Human thyroid cancer
Recommended dilution: 50-200    Predicted cell location: Cytoplasm
Positive control: Human brain
Recommended dilution: 50-200