Product overview
Description Anti-PPOX rabbit polyclonal antibody
Applications ELISA, IHC
Immunogen Fusion protein of human PPOX
Reactivity Human, Mouse, Rat
Content 0.54 mg/ml
Host species Rabbit
Ig class Immunogen-specific rabbit IgG
Purification Antigen affinity purification
Target information
Symbol PPOX
Full name protoporphyrinogen oxidase
Synonyms VP; PPO; V290M
Swissprot P50336
Target Background
This gene encodes the penultimate enzyme of heme biosynthesis, which catalyzes the 6-electron oxidation of protoporphyrinogen IX to form protoporphyrin IX. Mutations in this gene cause variegate porphyria, an autosomal dominant disorder of heme metabolism resulting from a deficiency in protoporphyrinogen oxidase, an enzyme located on the inner mitochondrial membrane. Alternatively spliced transcript variants encoding the same protein have been identified.
Anti-PPOX antibody Applications
Immunohistochemistry
Predicted cell location: Cytoplasm and Nucleus
Positive control: Human esophagus cancer
Recommended dilution: 30-150 Predicted cell location: Cytoplasm and Nucleus
Positive control: Human tonsil
Recommended dilution: 30-150