Anti-CYP1A2 antibody

Anti-CYP1A2 antibody

Cat. No.    JC162003
Package    25 μl/100 μl/200 μl
Storage    -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol

Product overview
Description                   Anti-CYP1A2 rabbit polyclonal antibody
Applications        ELISA, WB 
Immunogen               Synthetic peptide of human CYP1A2
Reactivity                 Human, Mouse
Content                     0.6 mg/ml
Host species               Rabbit
Ig class                  Immunogen-specific rabbit IgG
Purification                 Antigen affinity purification

Anti-CYP1A2 antibody
Target information
Symbol                 CYP1A2
Full name                 cytochrome P450, family 1, subfamily A, polypeptide 2
Synonyms    CP12; P3-450; P450(PA)
Swissprot    P05177

Target Background
This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. The protein encoded by this gene localizes to the endoplasmic reticulum and its expression is induced by some polycyclic aromatic hydrocarbons (PAHs), some of which are found in cigarette smoke. The enzyme's endogenous substrate is unknown; however, it is able to metabolize some PAHs to carcinogenic intermediates. Other xenobiotic substrates for this enzyme include caffeine, aflatoxin B1, and acetaminophen. The transcript from this gene contains four Alu sequences flanked by direct repeats in the 3' untranslated region.

Anti-CYP1A2 antibody
Applications
Western blotting
Predicted band size:58 kDa
Positive control:Mouse liver tissue 
Recommended dilution: 200-1000