Anti-HIST1H2AB antibody

Anti-HIST1H2AB antibody

Cat. No.     JC161744  
Package    25 μl/100 μl/200 μl
Storage    -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol

Product overview
Description                   Anti-HIST1H2AB rabbit polyclonal antibody
Applications        ELISA, WB, IHC 
Immunogen               Synthetic peptide of human HIST1H2AB
Reactivity                 Human, Mouse
Content                     0.2 mg/ml
Host species               Rabbit
Ig class                  Immunogen-specific rabbit IgG
Purification                 Antigen affinity purification

Anti-HIST1H2AB antibody
Target information
Symbol                 HIST1H2AB
Full name                 histone cluster 1, H2ab
Synonyms    H2A/m; H2AFM
Swissprot    P04908

Target Background
Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. This structure consists of approximately 146 bp of DNA wrapped around a nucleosome, an octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene is intronless and encodes a member of the histone H2A family. Transcripts from this gene lack polyA tails; instead, they contain a palindromic termination element. This gene is found in the large histone gene cluster on chromosome 6p22-p21.3.

Anti-HIST1H2AB antibody
Applications
Immunohistochemistry
Predicted cell location: Nucleus
Positive control: Human gasrtic cancer
Recommended dilution: 50-200    Predicted cell location: Nucleus
Positive control: Human thyroid cancer
Recommended dilution: 50-200