- ￥1500 - 2500
- HUABIO
- ET7108-06
- 浙江杭州
- 2025年07月15日
- WB,IHC-P,FC,IP
- Rabbit
- Human, Mouse, Rat
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- 详细信息
- 文献和实验
- 技术资料
- 靶点：
ELMO1
- 浓度：
1 mg/mL.
- 应用范围：
WB,IHC-P,FC,IP
- 宿主：
Rabbit
- 适应物种：
Human, Mouse, Rat
- 保质期：
1年
- 供应商：
Huabio
- 标记物：
Non-conjugated
- 保存条件：
Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles.
- 形态：
Liquid
- 亚型：
IgG
- 免疫原：
Synthetic peptide within C-terminal Human ELMO1 .
- 规格：
50μl/100μl
| 规格： | 50μl | 产品价格： | ￥1500.0 |
|---|---|---|---|
| 规格： | 100μl | 产品价格： | ￥2500.0 |
Elmo (engulfment and cell motility) proteins share similarity to C. elegans CED-12. The C. elegans genes ced-2, ced-5, ced-10 and ced-12, and their mammalian homologs, CRKII, DOCK1, RAC1 and ELMO, mediate cytoskeletal rear-rangements during phagocytosis of apoptotic cells as well as cell motility. Elmo1 associates with DOCK 180 and may influence phagocytosis and effect cell shape changes. Src family kinase-mediated tyrosine phosphorylation of Elmo1 influences signaling through Elmo1/Crk/DOCK 180 pathways. Elmo2 interacts directly with Rho G in a GTP-dependent manner and forms a ternary complex with DOCK 180 to induce activation of Rac 1. The Rho G-Elmo2-DOCK 180 pathway is required for activation of Rac 1 and cell spreading mediated by integrin, as well as for neurite outgrowth induced by nerve growth factor. Elmo3 acts in assocation with DOCK 180 and Crk II and may be required in complex with DOCK 180 to activate Rac/Rho small GTPases.
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ET7108-06·Anti-ELMO1 Antibody
￥1500 - 2500
