- ￥1600 - 2650
- HUABIO
- ET1705-50
- 浙江杭州
- 2025年07月09日
- WB,ICC/IF,IHC-P,IP
- Rabbit
- Human
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- 详细信息
- 文献和实验
- 技术资料
- 靶点：
ATM
- 浓度：
1 mg/mL.
- 应用范围：
WB,ICC/IF,IHC-P,IP
- 宿主：
Rabbit
- 适应物种：
Human
- 保质期：
1年
- 供应商：
Huabio
- 标记物：
Non-conjugated
- 保存条件：
Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles.
- 形态：
Liquid
- 亚型：
IgG
- 免疫原：
Synthetic phospho-peptide corresponding to residues surrounding Ser1981 of human ATM.
- 规格：
50μl/100μl
| 规格： | 50μl | 产品价格： | ￥1600.0 |
|---|---|---|---|
| 规格： | 100μl | 产品价格： | ￥2650.0 |
ATM serine/threonine kinase, symbol ATM, is a serine/threonine protein kinase that is recruited and activated by DNA double-strand breaks. It phosphorylates several key proteins that initiate activation of the DNA damage checkpoint, leading to cell cycle arrest, DNA repair or apoptosis. Several of these targets, including p53, CHK2, BRCA1, NBS1 and H2AX are tumor suppressors. The ATM-mediated DNA damage response consists of a rapid and a delayed response. The protein kinase ATM may also be involved in mitochondrial homeostasis, as a regulator of mitochondrial autophagy (mitophagy) whereby old, dysfunctional mitochondria are removed. Increased ATM activity also occurs in viral infection where ATM is activated early during dengue virus infection as part of autophagy induction and ER stress response.
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文献和实验该产品被引用文献
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文献支持
ET1705-50·Anti-ATM (phospho S1981) Antibody
￥1600 - 2650
