Product overview
Description Anti-BMPER rabbit polyclonal antibody
Applications ELISA, IHC
Immunogen Synthetic peptide of human BMPER
Reactivity Human, Mouse
Content 0.9 mg/ml
Host species Rabbit
Ig class Immunogen-specific rabbit IgG
Purification Antigen affinity purification
Target information
Symbol BMPER
Full name BMP binding endothelial regulator
Synonyms CV2; CV-2; CRIM3
Swissprot Q8N8U9
Target Background
This gene encodes a secreted protein that interacts with, and inhibits bone morphogenetic protein (BMP) function. It has been shown to inhibit BMP2- and BMP4-dependent osteoblast differentiation and BMP-dependent differentiation of the chondrogenic cells. Mutations in this gene are associated with a lethal skeletal disorder, diaphanospondylodysostosis.