Product overview
Description Anti-SPTB rabbit polyclonal antibody
Applications ELISA, IHC
Immunogen Synthetic peptide of human SPTB
Reactivity Human
Content 0.7 mg/ml
Host species Rabbit
Ig class Immunogen-specific rabbit IgG
Purification Antigen affinity purification
Target information
Symbol SPTB
Full name spectrin beta, erythrocytic
Synonyms EL3; HS2; SPH2; HSPTB1
Swissprot P11277
Target Background
This locus encodes a member of the spectrin gene family. Spectrin proteins, along with ankyrin, play a role in cell membrane organization and stability. The protein encoded by this locus functions in stability of erythrocyte membranes, and mutations in this gene have been associated with spherocytosis type 2, hereditary elliptocytosis, and neonatal hemolytic anemia. Alternatively spliced transcript variants have been described.