Anti-MMP16 antibody

Anti-MMP16 antibody

Cat. No.     JC220992
Package    25 μl/100 μl/200 μl
Storage    -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol

Product overview
Description                   Anti-MMP16 rabbit polyclonal antibody
Applications        ELISA, IHC 
Immunogen               Fusion protein of human MMP16
Reactivity                 Human, Mouse, Rat
Content                     0.3 mg/ml
Host species               Rabbit
Ig class                  Immunogen-specific rabbit IgG
Purification                 Antigen affinity purification

Target information
Symbol                 MMP16
Full name                 matrix metallopeptidase 16 (membrane-inserted)
Synonyms    MMP-X2; C8orf57; MT-MMP2; MT-MMP3; MT3-MMP
Swissprot    P51512

Target Background
Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. The encoded protein activates MMP2 by cleavage. This gene was once referred to as MT-MMP2, but was renamed as MT-MMP3 or MMP16.

Applications
Immunohistochemistry
Predicted cell location: Cytoplasm
Positive control: Human thyroid cancer
Recommended dilution: 25-100    Predicted cell location: Cytoplasm
Positive control: Human brain
Recommended dilution: 25-100