Anti-MMP15 antibody

Anti-MMP15 antibody

Cat. No.     JC220991
Package    25 μl/100 μl/200 μl
Storage    -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol

Product overview
Description                   Anti-MMP15 rabbit polyclonal antibody
Applications        ELISA, WB 
Immunogen               Fusion protein of human MMP15
Reactivity                 Human, Mouse
Content                     0.3 mg/ml
Host species               Rabbit
Ig class                  Immunogen-specific rabbit IgG
Purification                 Antigen affinity purification

Target information
Symbol                 MMP15
Full name                 matrix metallopeptidase 15 (membrane-inserted)
Synonyms    MTMMP2, SMCP-2, MT2-MMP
Swissprot    P51511

Target Background
Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. However, the protein encoded by this gene is a member of the membrane-type MMP (MT-MMP) subfamily; each member of this subfamily contains a potential transmembrane domain suggesting that these proteins are expressed at the cell surface rather than secreted.

Applications
Western blotting
Predicted band size:76 kDa
Positive control:Mouse heart tissue 
Recommended dilution: 200-1000