Product overview Description Anti-H3F3C rabbit polyclonal antibody
Applications ELISA, WB
Immunogen Fusion protein of human H3F3C
Reactivity Human, Mouse, Rat
Content 0.2 mg/ml
Host species Rabbit
Ig class Immunogen-specific rabbit IgG
Purification Antigen affinity purification
Target information Symbol H3F3C
Full name H3 histone, family 3C
Synonyms H3.5
Swissprot Q6NXT2
Target Background Eukaryotic histones are basic and water soluble nuclear proteins that form hetero-octameric nucleosome particles by wrapping 146 base pairs of DNA in a left-handed super-helical turn sequentially to form chromosomal fiber. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form the octamer; formed of two H2A-H2B dimers and two H3-H4 dimers, forming two nearly symmetrical halves by tertiary structure. Over 80% of nucleosomes contain the linker Histone H1, derived from an intronless gene, that interacts with linker DNA between nucleosomes and mediates compaction into higher order chromatin.
Applications Western blotting
Predicted band size:15 kDa
Positive control:Human fetal brain tissue and Hela cells
Recommended dilution: 200-1000