Anti-NRG2 antibody

Anti-NRG2 antibody

Cat. No.     JC161359
Package    25 μl/100 μl/200 μl
Storage    -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol

Product overview
Description                   Anti-NRG2 rabbit polyclonal antibody
Applications        ELISA, IHC 
Immunogen               Synthetic peptide of human NRG2
Reactivity                 Human, Mouse, Rat
Content                     0.2 mg/ml
Host species               Rabbit
Ig class                  Immunogen-specific rabbit IgG
Purification                 Antigen affinity purification

Anti-NRG2 antibody
Target information
Symbol                 NRG2
Full name                 neuregulin 2
Synonyms    DON1; HRG2; NTAK
Swissprot    O14511

Target Background
This gene encodes a novel member of the neuregulin family of growth and differentiation factors. Through interaction with the ERBB family of receptors, this protein induces the growth and differentiation of epithelial, neuronal, glial, and other types of cells. The gene consists of 12 exons and the genomic structure is similar to that of neuregulin 1, another member of the neuregulin family of ligands. The products of these genes mediate distinct biological processes by acting at different sites in tissues and eliciting different biological responses in cells. This gene is located close to the region for demyelinating Charcot-Marie-Tooth disease locus, but is not responsible for this disease. Alternative transcript variants encoding distinct isoforms have been described.

Anti-NRG2 antibody
Applications
Immunohistochemistry
Predicted cell location: Secreted
Positive control: Human esophagus cancer
Recommended dilution: 20-100    Predicted cell location: Secreted
Positive control: Human liver cancer
Recommended dilution: 20-100