Anti-LIN28B antibody

Anti-LIN28B antibody

Cat. No.  JC161340      
Package    25 μl/100 μl/200 μl
Storage    -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol

Product overview
Description                   Anti-LIN28B rabbit polyclonal antibody
Applications        ELISA, WB 
Immunogen               Synthetic peptide of human LIN28B
Reactivity                 Human, Mouse
Content                     0.3 mg/ml
Host species               Rabbit
Ig class                  Immunogen-specific rabbit IgG
Purification                 Antigen affinity purification

Anti-LIN28B antibody
Target information
Symbol                 LIN28B
Full name                 lin-28 homolog B (C. elegans)
Synonyms    CSDD2
Swissprot    Q6ZN17

Target Background
The protein encoded by this gene belongs to the lin-28 family, which is characterized by the presence of a cold-shock domain and a pair of CCHC zinc finger domains. This gene is highly expressed in testis, fetal liver, placenta, and in primary human tumors and cancer cell lines. It is negatively regulated by microRNAs that target sites in the 3' UTR, and overexpression of this gene in primary tumors is linked to the repression of let-7 family of microRNAs and derepression of let-7 targets, which facilitates cellular transformation. [provided by RefSeq, Jun 2012]

Anti-LIN28B antibody
Applications
Western blotting
Predicted band size:27 kDa
Positive control:Mouse liver tissue and k562 cells, hela and 293T cells 
Recommended dilution: 500-2000