Anti-ATG4A antibody

Anti-ATG4A antibody
Cat. No.     JC161325     
Package    25 μl/100 μl/200 μl
Storage    -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol

Product overview
Description                   Anti-ATG4A rabbit polyclonal antibody
Applications        ELISA, WB, IHC 
Immunogen               Synthetic peptide of human ATG4A
Reactivity                 Human
Content                     0.3 mg/ml
Host species               Rabbit
Ig class                  Immunogen-specific rabbit IgG
Purification                 Antigen affinity purification

Anti-ATG4A antibody
Target information
Symbol                 ATG4A
Full name                 autophagy related 4A, cysteine peptidase
Synonyms    APG4A; AUTL2
Swissprot    Q8WYN0

Target Background
Autophagy is the process by which endogenous proteins and damaged organelles are destroyed intracellularly. Autophagy is postulated to be essential for cell homeostasis and cell remodeling during differentiation, metamorphosis, non-apoptotic cell death, and aging. Reduced levels of autophagy have been described in some malignant tumors, and a role for autophagy in controlling the unregulated cell growth linked to cancer has been proposed. This gene encodes a member of the autophagin protein family. The encoded protein is also designated as a member of the C-54 family of cysteine proteases. Transcript variants that encode distinct isoforms have been identified.

Anti-ATG4A antibody
Applications
Immunohistochemistry
Predicted cell location: Cytoplasm
Positive control: Human colon cancer
Recommended dilution: 50-200    Predicted cell location: Cytoplasm
Positive control: Human gastric cancer
Recommended dilution: 50-200