Product overview
Description Anti-ATG4B rabbit polyclonal antibody
Applications ELISA, IHC
Immunogen Synthetic peptide of human ATG4B
Reactivity Human
Content 0.5 mg/ml
Host species Rabbit
Ig class Immunogen-specific rabbit IgG
Purification Antigen affinity purification
Anti-ATG4B antibody Target information
Symbol ATG4B
Full name autophagy related 4B, cysteine peptidase
Synonyms APG4B; AUTL1
Swissprot Q9Y4P1
Target Background
Autophagy is the process by which endogenous proteins and damaged organelles are destroyed intracellularly. Autophagy is postulated to be essential for cell homeostasis and cell remodeling during differentiation, metamorphosis, non-apoptotic cell death, and aging. Reduced levels of autophagy have been described in some malignant tumors, and a role for autophagy in controlling the unregulated cell growth linked to cancer has been proposed. This gene encodes a member of the autophagin protein family. The encoded protein is also designated as a member of the C-54 family of cysteine proteases. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
Anti-ATG4B antibody Applications
Immunohistochemistry
Predicted cell location: Cytoplasm
Positive control: Human brain
Recommended dilution: 50-200 Predicted cell location: Cytoplasm
Positive control: Human liver cancer
Recommended dilution: 50-200