Product overview
Description Anti-XAF1 rabbit polyclonal antibody
Applications ELISA, IHC
Immunogen Synthetic peptide of human XAF1
Reactivity Human
Content 0.7 mg/ml
Host species Rabbit
Ig class Immunogen-specific rabbit IgG
Purification Antigen affinity purification
Target information
Symbol XAF1
Full name XIAP associated factor 1
Synonyms BIRC4BP; XIAPAF1; HSXIAPAF1
Swissprot Q6GPH4
Target Background
This gene encodes a protein which binds to and counteracts the inhibitory effect of a member of the IAP (inhibitor of apoptosis) protein family. IAP proteins bind to and inhibit caspases which are activated during apoptosis. The proportion of IAPs and proteins which interfere with their activity, such as the encoded protein, affect the progress of the apoptosis signaling pathway. Multiple transcript variants encoding different isoforms have been found for this gene.