Anti-SLC12A7 antibody

Anti-SLC12A7 antibody

Cat. No.     JC264322
Package    25 μl/100 μl/200 μl
Storage    -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol

Product overview
Description                   Anti-SLC12A7 rabbit polyclonal antibody
Applications        ELISA, IHC 
Immunogen               Synthetic peptide of human SLC12A7
Reactivity                 Human
Content                     0.96 mg/ml
Host species               Rabbit
Ig class                  Immunogen-specific rabbit IgG
Purification                 Antigen affinity purification

Target information
Symbol                 SLC12A7
Full name                 solute carrier family 12 member 7
Synonyms    KCC4
Swissprot    Q9Y666

Target Background
Mediates electroneutral potassium-chloride cotransport when activated by cell swelling. May mediate K+ uptake into Deiters' cells in the cochlea and contribute to K+recycling in the inner ear. Important for the survival of cochlear outer and inner hair cells and the maintenance of the organ of Corti. May be required for basolateral Cl-extrusion in the kidney and contribute to renal acidification (By similarity).

Applications
Immunohistochemistry
Predicted cell location: Cytoplasm
Positive control: Human tonsil
Recommended dilution: 25-100    Predicted cell location: Cytoplasm
Positive control: Human cervical cancer
Recommended dilution: 25-100
            
The image on the left is immunohistochemistry of paraffin-embedded Human tonsil tissue using ml264322(SLC12A7 Antibody) at dilution 1/35, on the right is treated with synthetic peptide. (Original magnification: ×200)    The image on the left is immunohistochemistry of paraffin-embedded Human cervical cancer tissue using ml264322(SLC12A7 Antibody) at dilution 1/35, on the right is treated with synthetic peptide. (Original magnification: ×200)

ELISA
Recommended dilution: 5000-10000