Product overview
Description Anti-HNF1B rabbit polyclonal antibody
Applications ELISA, IHC
Immunogen Synthetic peptide of human HNF1B
Reactivity Human, Mouse, Rat
Content 0.9 mg/ml
Host species Rabbit
Ig class Immunogen-specific rabbit IgG
Purification Antigen affinity purification
Anti-HNF1B antibody Target information
Symbol HNF1B
Full name HNF1 homeobox B
Synonyms FJHN; HNF2; LFB3; TCF2; HPC11; LF-B3; MODY5; TCF-2; VHNF1; HNF-1B; HNF1beta
Swissprot P35680
Target Background
This gene encodes a member of the homeodomain-containing superfamily of transcription factors. The protein binds to DNA as either a homodimer, or a heterodimer with the related protein hepatocyte nuclear factor 1-alpha. The gene has been shown to function in nephron development, and regulates development of the embryonic pancreas. Mutations in this gene result in renal cysts and diabetes syndrome and noninsulin-dependent diabetes mellitus, and expression of this gene is altered in some types of cancer. Multiple transcript variants encoding different isoforms have been found for this gene.
Anti-HNF1B antibody Applications
Immunohistochemistry
Predicted cell location: Nucleus
Positive control: Human colon cancer
Recommended dilution: 100-300 Predicted cell location: Nucleus
Positive control: Human lung cancer
Recommended dilution: 100-300