Product overview
Description Anti-STARD5 rabbit polyclonal antibody
Applications ELISA, IHC
Immunogen Synthetic peptide of human STARD5
Reactivity Human, Mouse
Content 0.4 mg/ml
Host species Rabbit
Ig class Immunogen-specific rabbit IgG
Purification Antigen affinity purification
Target information
Symbol STARD5
Full name StAR-related lipid transfer (START) domain containing 5
Synonyms
Swissprot Q9NSY2
Target Background
Cholesterol homeostasis is regulated, at least in part, by sterol regulatory element (SRE)-binding proteins (e.g., SREBP1; MIM 184756) and by liver X receptors (e.g., LXRA; MIM 602423). Upon sterol depletion, LXRs are inactive and SREBPs are cleaved, after which they bind promoter SREs and activate genes involved in cholesterol biosynthesis and uptake.