Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit, Sheep,
适应物种:
Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit, Sheep,
免疫原:
详见说明书
亚型:
IGg
形态:
粉末、液体、冻干粉
应用范围:
ICC=1:50-200 IF=1:50-200
浓度:
1mg/ml
保存条件:
-20 °C
规格:
100ul
FITC标记的MS4A15蛋白抗体
英文名称
Anti-MS4A15/FITC
中文名称
FITC标记的MS4A15蛋白抗体
别 名
FLJ34527; Hypothetical protein MGC35295; M4A15_HUMAN; Membrane spanning 4 domains subfamily A member 15; Membrane-spanning 4-domains subfamily A member 15; MGC35295; MS4A15.
规格价格
100ul/2980元 购买 大包装/询价
说 明 书
100ul
研究领域
细胞生物 跨膜蛋白 细胞膜蛋白
抗体来源
Rabbit
克隆类型
Polyclonal
交叉反应
Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit, Sheep,
产品应用
ICC=1:50-200 IF=1:50-200 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
分 子 量
25kDa
性 状
Lyophilized or Liquid
浓 度
1mg/ml
免 疫 原
KLH conjugated synthetic peptide derived from human MS4A15
亚 型
IgG
纯化方法
affinity purified by Protein A
储 存 液
0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件
Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
产品介绍
background: MS4A (membrane-spanning 4-domain family, subfamily A) is a large family of proteins that includes at least 26 members in mouse and humans. Flanked by amino- and carboxyl- cytoplasmic regions, MS4A family members contain four highly conserved transmembrane domains. CD20, the most well-known MS4A family member, is a B-cell-specific molecule that functions as a calcium-permeable cation channel and is known to accelerate the G0 to G1 progression induced by IGF-1. MS4A15 (membrane-spanning 4-domains, subfamily A, member 15) is a 240 amino acid multi-pass membrane protein that exists as two alternatively spliced isoforms. The gene encoding MS4A15 maps to human chromosome 11, which houses over 1,400 genes and comprises nearly 4% of the human genome. Jervell and Lange-Nielsen syndrome, Jacobsen syndrome, Niemann-Pick disease, hereditary angioedema and Smith-Lemli-Opitz syndrome are associated with defects in genes that maps to chromosome 11.
Function: May be involved in signal transduction as a component of a multimeric receptor complex.
Subcellular Location: Membrane.
Similarity: Belongs to the MS4A family.
Database links:
Entrez Gene: 219995 Human
Entrez Gene: 545279 Mouse
SwissProt: Q8N5U1 Human
SwissProt: Q3UPL6 Mouse
Unigene: 207465 Human
Unigene: 329729 Mouse
Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.