Anti-PIF1 antibody

Anti-PIF1 antibody

Cat. No.    JC160601        
Package    25 μl/100 μl/200 μl
Storage    -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol

Product overview
Description                   Anti-PIF1 rabbit polyclonal antibody
Applications        ELISA, WB, IHC 
Immunogen               Synthetic peptide of human PIF1
Reactivity                 Human, Mouse
Content                     0.96 mg/ml
Host species               Rabbit
Ig class                  Immunogen-specific rabbit IgG
Purification                 Antigen affinity purification

Anti-PIF1 antibody
Target information
Symbol                 PIF1
Full name                 PIF1 5'-to-3' DNA helicase
Synonyms    PIF; C15orf20
Swissprot    Q9H611

Target Background
This gene encodes a DNA-dependent adenosine triphosphate (ATP)-metabolizing enzyme that functions as a 5' to 3' DNA helicase. The encoded protein can resolve G-quadruplex structures and RNA-DNA hybrids at the ends of chromosomes. It also prevents telomere elongation by inhibiting the actions of telomerase. Alternative splicing and the use of alternative start codons results in multiple isoforms that are differentially localized to either the mitochondria or the nucleus.

Anti-PIF1 antibody
Applications
Immunohistochemistry
Predicted cell location: Nucleus
Positive control: Human ovarian cancer
Recommended dilution: 25-100    Predicted cell location: Nucleus
Positive control: Human gastric cancer
Recommended dilution: 25-100