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- 详细信息
- 文献和实验
- 技术资料
- 供应商:
上海机纯实业有限公司
- 库存:
大量
- 克隆性:
多克隆
- 保质期:
12个月
- 抗体英文名:
Anti-SUMO2/SUMO3/SUMO4 antibody
- 宿主:
Rabbit
- 适应物种:
人/动物/植物
- 应用范围:
ELISA, WB
- 浓度:
0.4 mg/ml
- 保存条件:
-20°C
- 规格:
25 μl/100 μl/200 μl
Cat. No. JC160378
Package 25 μl/100 μl/200 μl
Storage -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Product overview
Description Anti-SUMO2/SUMO3/SUMO4 rabbit polyclonal antibody
Applications ELISA, WB, IHC
Immunogen Synthetic peptide of human SUMO2/SUMO3/SUMO4
Reactivity Human, Mouse
Content 0.4 mg/ml
Host species Rabbit
Ig class Immunogen-specific rabbit IgG
Purification Antigen affinity purification
Anti-SUMO2/SUMO3/SUMO4 antibody
Target information
Symbol SUMO2/SUMO3/SUMO4
Full name SMT3 suppressor of mif two 3 homolog 2/3/4 (S. cerevisiae)
Synonyms SMT3A, Smt3B, SMT3H1, SUMO-3; HSMT3, SMT3B, SUMO3, Smt3A, SMT3H2; IDDM5, SMT3H4, SUMO-4, dJ281H8.4
Swissprot P61956/P55854/Q6EEV6
Target Background
This gene encodes a protein that is a member of the SUMO (small ubiquitin-like modifier) protein family. It functions in a manner similar to ubiquitin in that it is bound to target proteins as part of a post-translational modification system. However, unlike ubiquitin which targets proteins for degradation, this protein is involved in a variety of cellular processes, such as nuclear transport, transcriptional regulation, apoptosis, and protein stability. It is not active until the last two amino acids of the carboxy-terminus have been cleaved off. Numerous pseudogenes have been reported for this gene. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
Anti-SUMO2/SUMO3/SUMO4 antibody
Applications
Immunohistochemistry
Predicted cell location: Cytoplasm, Nucleus
Positive control: Human colon cancer
Recommended dilution: 100-300 Predicted cell location: Cytoplasm, Nucleus
Positive control: Human thyroid cancer
Recommended dilution: 100-300
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文献和实验Generation of Antibody Molecules Through Antibody Engineering
been overcome to a large extent using genetic-engineering techniques to produce chimeric mouse/human and completely human antibodies. Such an approach is particularly suitable because of the domain structure of the antibody molecule ( 2 ), where functional
The importance of antibody molecules was first recognized in the 1890s, when it was shown that immunity to tetanus and diphtheria was caused by antibodies against the bacterial exotoxins (1 ). Around the same time, it was shown that antisera
General comments: Antibodies, like most proteins, do not like to be freeze-thawed. Avoid repetitive freezing of your solution. The best way to store your antibody is to keep a high protein concentration (>1 mg/ml), add some protease
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